Always be prepared to split on an off beat, for sure. It doesn't matter what bass you're on, if you can count an off beat, then counting a downbeat won't be an issue for you.
Also, not all writing puts second bass on an off beat, you could just as easily turn the writing around and put 2 on the down and ands, and 1 can be chugging along on the e's and a's. Be prepared all around, and just flat out be able to count.
Hope that helped.
B
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